REPORT/RECOMMENDATION TO THE BOARD OF SUPERVISORS
OF SAN BERNARDINO COUNTY
AND RECORD OF ACTION
April 9, 2024
FROM
WILLIAM L. GILBERT, Director, Arrowhead Regional Medical Center
SUBJECT
Title
Amendment to Subaward Agreement with the University of Cincinnati on Behalf of its National Institute of Health StrokeNet National Coordinating Center
End
RECOMMENDATION(S)
Recommendation
Approve Amendment No. 1, including a non-standard term, to Revenue Subaward Agreement No. 20-572 with the University of Cincinnati on behalf of its National Institutes of Health StrokeNet National Coordinating Center relating to studies on intracerebral hemorrhage patients, amending the name of the pass-through entity and the language relating to modifications to the contract, and extending the term for an additional two years, for a total period of July 14, 2020 through April 30, 2026.
(Presenter: William L. Gilbert, Director, 580-6150)
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COUNTY AND CHIEF EXECUTIVE OFFICER GOALS & OBJECTIVES
Promote the Countywide Vision.
Provide for the Safety, Health and Social Service Needs of County Residents.
FINANCIAL IMPACT
Approval of this item will not result in the use of Discretionary General Funding (Net County Cost) as there is no cost to the County to participate in the clinical trial studies and results in revenue to the County. The University of Cincinnati on behalf of its National Institutes of Health (NIH) StrokeNet National Coordinating Center will pass through funding to the Arrowhead Regional Medical Center (ARMC) of $10,810 per participating patient for clinical trials. This funding does not require a match from the County. The amount of revenue received will be dependent on the number of eligible patients to participate in the clinical trials. Sufficient appropriation and revenue are included in the ARMC 2023-24 budget and will be included in future recommended budgets.
BACKGROUND INFORMATION
Approval of Recommendation No. 1 will allow ARMC to continue its participation in the Anticoagulation in Intracerebral Brain Hemorrhage (ICH) Survivors for Prevention and Recovery (ASPIRE) study through the NIH for an additional two years, extending the term of Agreement No. 20-572 (Agreement) from April 30, 2024, through April 30, 2026, for a total contract period of July 14, 2020 through April 30, 2026. It also amends the pass-through entity with whom the County is contracted for the ASPIRE study from the “National Coordinating Center - University of Cincinnati on behalf of Yale University” to the “University of Cincinnati on behalf of its NIH StrokeNet National Coordinating Center” (University).
The Amendment contains the following non-standard term:
1. The Amendment enables the University to extend the term of the Agreement with advance notice unless the County objects within 14 days after receipt of the notice.
• The County standard contract requires the execution of an amendment signed by all parties to modify the terms of the contract.
• Potential Impact: ARMC will need to be mindful of any requested extensions by the University and object to any requested extensions and require that the requested extension be in the form of an amendment approved by the Board. It should be noted, however, that the County has the right to terminate the Agreement at any time with 30 days written notice.
On July 14, 2020 (Item No. 11), the Board of Supervisors approved Subaward Agreement No. 20-572 with the University for ARMC to participate in the ASPIRE study related to ICH patients, for revenue amounts not to exceed $10,810 per participating patient, for the performance period of July 14, 2020 through April 30, 2024.
The NIH funds small and large clinical trials and research studies to advance acute stroke treatment, stroke prevention, and recovery and rehabilitation following a stroke across the lifespan. Yale University was awarded the ASPIRE study grant, which then contracted with the University (acting as the national coordinating center) to issue subawards to participating institutions, including ARMC.
The subaward with the University provides for the safety, health and social services needs of county residents through the study of the effectiveness of anti-cholesterol drugs and anti-coagulation drugs in the prevention of strokes. ARMC is a certified Comprehensive Stroke Center and is also a member of the NIH StrokeNet, which enables the hospital to participate in national research studies.
ARMC recommends approval of this Amendment to support and enhance the work of ARMC’s Stroke Program.
PROCUREMENT
Not applicable.
REVIEW BY OTHERS
This item has been reviewed by County Counsel (Charles Phan, Deputy County Counsel, 387- 5455) on March 14, 2024; ARMC Finance (Chen Wu, Finance and Budget Officer, 580-3165) on March 15, 2024; Finance (Jenny Yang, Administrative Analyst, 387-4884) on March 19, 2024; and County Finance and Administration (Valerie Clay, Deputy Executive Officer, 387- 5423) on March 20, 2024.